BioPAT® Spectro
Quality by Design tool for detecting the full potential of Raman spectroscopy
The bioprocess industry has always recognized the significant potential of Raman spectroscopy - it provides significantly more process data, leading to more robust processes and resulting in high and consistent quality products. However, the use of this potential in practice has been a problem due to the need to collect and consolidate data from different sources in order to build models.
From now on, thanks to the BioPAT® Spectro Process Analyzer, this approach has changed.
BioPAT® Spectro in Ambr® and Flexsafe STR®
BioPAT® Spectro in Ambr® 15 and Ambr® 250 high throughput bioreactors
BioPAT® Spectro in Ambr® 15 and Ambr® 250 High Throughput bioreactors reduces modeling time by 50%, which can result in up to 95% reduction in operator involvement and up to 80% savings in media costs compared to conventional modeling.
- enables QbD access in high-throughput process development, simultaneously measuring several analytes during (DoE)
- offers fully automated data consolidation and contextualization of Raman spectral data with all Ambr® software process data
- consolidated data files can be easily transferred to SIMCA® software, where more design space means more robust models than was previously possible
BioPAT® Spectro single-use connector in Flexsafe STR® bags
The BioPAT® Spectro single-use connector is fully integrated into Flexsafe STR® bags.
- scalable platform with standardized optical probe interface via Ambr® and Flexsafe STR® facilitates model transfer
- a fully integrated and qualified disposable connection reduces installation time and reduces the risk of contamination
- the use of a flow cell separates the measurement from interference through process conditions such as gas generation and mixing
BioPAT® Spectro can be used for process development and commercial production
Process development
Easier and faster modeling, high-throughput process development with Raman spectroscopy
Commercial production
Single-use integration of Raman spectroscopy with faster set-up time, reduced risk of contamination and efficient transfer from process development
