Ambr® 15 Cell Culture | Multi-Parallel Bioreactor
Automated bioreactor system with high throughput
Ambr® 15 Cell Culture is a high throughput, automated bioreactor system for 24 or 48 parallel cultivations with a working volume of 10-15 ml of microbioreactor. Offering new functionality, a high level of flexibility and improved performance, the new generation system is suitable for applications that include:
- selection of clones
- development of media and animal feed
- process optimization at an early stage
- screening under perfusion mimicry conditions.
Ambr® 15 Cell culture system features
Ambr® 15 is an industry-standard microbioreactor system used in laboratories around the world. It offers cost-effective experimentation by saving space, capital, labor, media and consumables. Integrated metabolite analysis accelerates the implementation of the Quality by Design (QbD) principle.
- new fluid handling capabilities
- new cell culture design
- a new software application for selecting clones.
Ambr® 15 microbioreactor vessel
It mimics the properties of laboratory bioreactors to enable optimal cell growth, productivity and product quality:
- 10 - 15 ml of microbioreactor working volume
- disposable pH and DO sensors
- integrated rotor with blades
- liquid addition and sampling opening
- available with temperature compensation for application at lower temperatures, experiments below 33° C.
Ambr® analysis module
The analysis module provides additional options for in-line pH measurement and, optionally, Raman spectroscopy for Ambr® 15 and Ambr® 250 bioreactors. PH measurement automates the initial calibration of the pH sensor for the bioreactor and subsequent re-calibration in the process, eliminating operator time pH measurement, data transfer and recalibration of the pH sensor in the bioreactor.
Video content
Ambr® 15 Cell Culture emits the characteristics of conventional micro-scale bioreactors (10 ml - 15 ml) using single-use microbioreactors under the supervision of an automated workstation. The system enables rapid assessment of microbiological cultures of multiple bioreactors, increasing productivity in cell line development - with significant savings in material and labor.
