PEIpro® is the leading PEI-based DNA transfection reagent that offers flexibility and scalability to develop a robust and sustainable viral vector manufacturing process. PEIpro® benefits from extensive research in PEI polymer chemistry and formulation to achieve the highest transfection efficiency in adherent and suspension cell culture systems.

PEIpro® allows a smooth transition from initial process development
to large-scale manufacturing of therapeutic viral vectors with three quality grades available: PEIpro®, PEIpro®-HQ, and PEIpro®-GMP. PEIpro®-GMP is the highest quality grade PEI-based reagent on the market and is provided with full regulatory documentation to support drug approvals.

Key features

  • Gold standard reagent - optimized PEI-based transfection reagent for scalable viral vector production
  • Reproducible - equivalent viral vector production guaranteed through three quality grades
  • GMP-Grade - manufactured in compliance with
    ICH Q7 guidelines
  • Residual Test - proprietary residual test to mitigate
    risks and ensure patient safety

PEIpro® meets your quality requirements

CharacteristicsPEIpro®PEIpro®-HQPEIpro®-GMP
Recommended useDiscovery to process developmentPre-clinical phaseClinical trials and commercialization
Quality gradeResearch use onlyHighly qualified gradecGMP grade
Packaging and sizeBottle: 1,5 mL | 10 mL | 100 mL | 1 LBottle: 100 mL | 1 L10 x bottle 10 mL | Bottle: 100 mL | Bag: 1 L
Fill and finish manufacturing
Process
Filtration 0.22 µmFiltration 0.22 µmSterile filtration, Validated aseptic process, Simulations
AuditISO 9001:2015ISO 9001:2015According to ICH Q7, Eudralex Vol 4, Part II and Annex I
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* More information about PEIpro® transfection agents can be found in the Product Datasheet.

Datasheet: PEIpro® Transfection Reagent For Small To Large Scale Viral Vector Production
Flyer: PEIpro® DNA transfection kit for virus production
Poster: Addressing Large Scale Manufacturing Of Clinical Grade Viral Vectors Using An Optimized PEI Based Transfection Proces