FectoVIR®-LV transfection reagents - Sartorius Croatia

FectoVIR®-LV transfection reagents

FectoVIR®-LV is the next generation of transfection reagent, free of animal component, designed to improve LV productivity in HEK-293 cell systems.
Price: On request

Lentiviral vectors are recognized to be the carrier of choice for allogenic or autologous cell therapies (such as CAR-T) because of its capacity to permanently integrate viral genome into host cell DNA. To produce those vectors, cell therapy producers generally use a transient transfection system that is scaled-up during process development phases.FectoVIR®-LV is made for large scale manufacturing with reduction of the complexation volume and increased complex stability. The FectoVIR®-LV benefits allow to increase number of doses produced per batch to treat more patient, while decreasing LV manufacturing costs.

Key benefits

  • Productivity - reach the highest Lentiviral vectors titers in suspension systems
  • Cost-Effectiveness - reduce your cost per batch with high titers and low DNA consumption
  • Scalability - produce at large scale with low complexation volume and long complex stability
  • Time-Saving - use DOE service to help you optimizing your process in a record time

Specifications:

Source: www.sartorius.com

Application Notes: Optimizing CAR-T Cell Generation Using e-Zyvec DNA Assembly And FectoVIR®-LV Technology
Datasheet: Fectovir®-LV Transfection Reagent | Lentiviral Vector Manufacturing
Datasheet: Fectovir® TM LV Transfection Reagent Protocol For Lentiviral Vector Production In Suspension HEK 293
Poster: Next-generation Transfection Reagent for Large Scale Therapeutic Lentiviral Vector Production

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