Syringeless filters

Sample preparation by clarification is an essential first step for almost all analytical techniques. Sample preparation by clarification is particularly important for techniques such as high-pressure liquid chromatography (HPLC). However, HPLC today presents some challenges: it requires precise removal of particles (from small volumes) that must pass through filters that do not add extractable or leachable substances to the mixture, which can complicate analysis. The process must be quick and very simple. Sartorius' innovation led to the development of a new, easy-to-use unit for modern HPLC needs - the Claristep® system with the base station and filter units.

Claristep® syringeless filtration station

The Claristep^® Station consists of a base, lid and exchangeable tray for easy and accurate positioning of sample vials and Claristep^® Filter units. The patent-pending design features unique grooves in the station lid and matching guide ridges on Claristep^® Filter units to enable intuitively correct alignment and convenient handling.

process up to 8 samples simultaneously
no syringe required
no need for a vacuum source or power supply
for low sample volumes ranging from 60 μL to 600 μL

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Claristep® syringeless filtration units

Major benefits of Claristep^® Filter units include extremely short contact times between samples and corresponding filters and caps. This ensures optimal, contamination-free results. Filtered liquids are collected in your choice of 12 × 32 mm outer diameter vials, based on the analytical method to be performed.

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What do you need to know about syringeless filters?

Yes. We recommend processing Claristep^® Filter units with the Claristep^® Station. Claristep^® Station is comprised of a station and one exchangeable Claristep^® Tray. The Claristep^® Tray can be purchased separately to order the number of trays needed for sample clarification.

Yes. In addition to Claristep^® Filter units and Claristep^® Station, you will need 12 + 32 mm sample vials and caps. Sartorius does not sell 12 + 32 mm vials, which are available in many configurations (clear glass, brown glass, PP, other plastics, with/without insert, crimp-top, screw-cap, snap-cap, etc.). They are offered by many companies and distributors.

Yes. In principle it is possible to manually use one Claristep^® Filter unit for clarification of one sample. However, consider that clarification has been optimized for use with Claristep^® Station. Without this station and tray, Sartorius cannot guarantee optimal clarification results.

The tray is optimized for holding 12 + 32 mm vials. More important, the Claristep^® Filter units positioned on top of the vials are not in direct contact with these vials. As a result, if glass vials are used, they are not exposed directly to the pressure applied by the station lid to close Claristep^® Filter units. Therefore, this minimizes the risk of glass breakage.

Currently no. Claristep^® Filter units will be launched with a choice of 0.2 μm and 0.45 μm pore size regenerated cellulose (RC) membranes. RC is suitable for nearly any preparation steps requiring filtration of aqueous and solvent samples. The only limitations are pH values of less than 3. Only strong acids cannot be processed using RC membranes

The effective filtration area is 0.74 cm2. We have optimized the ratio of filtration area to sample volume and therefore offer high filtration capacity, while minimizing the hold-up volume.