HPLC Chromatographic Systems

Hipersep® Flowdrive is a platform of preparative HPLC chromatography systems designed for the purification of peptides, oligonucleotides, insulin and other small molecules.

Preparative HPLC Chromatographic Systems

  • High configuration flexibility
  • Sanitary configuration and design
  • Compact and ergonomic design
  • Wide flow rate range
  • Fully automated system

The increasingly diverse drug development pipelines introduce new manufacturing requirements, such as high-temperature processes, compact and flexible equipment that is easy to clean. The Hipersep® Flowdrive platform is part of preparative HPLC systems designed for the purification of peptides, oligonucleotides, insulin, and other small molecules.

Hipersep® Flowdrive PilotHipersep® Flowdrive Process MHipersep® Flowdrive Process LHipersep® Flowdrive XXL
Scale ManufacturingClinicalClinical / CommercialClinical / CommercialCommercial
Flow Rate Range6-90 L/h60-500 L/h or
20-200 L/h (Low Flow Version)
300-1600 L/h1000-2500 L/h
Max Pressure100 bars100 bars100 bars70 bars
Typical Column Diameter50/80/110/150 mm110/150/200/300/450 mm300/450/590/800 mm800/1000 mm
Sanitary Design*NoYesYesNo
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Analytical HPLC Chromatographic Systems

At-Line HPLC analytical chromatography using CIM® Monolith technology

Using CIMac™ analytical columns, the PATfix® HPLC system provides online analysis for impurity control and critical quality attributes using HPLC fingerprinting. CIMac™ analytical columns combine all the characteristics of CIM® monoliths at an analytical level. They are the perfect tool for process monitoring and control, making them ideal for Process Analytical Technology (PAT). With bio-inert ceramic pump heads and flow rates of up to 10 mL per minute, the PATfix® is designed to manage analytical parameters for a wide range of biological products.