HEA HyperCel | Mixed-Mode Chromatography Resins - Sartorius Croatia

HEA HyperCel | Mixed-Mode Chromatography Resins

HEA HyperCel is a mixed-mode resin with a less hydrophobic hexylamine ligand that enables protein binding at moderate salt concentrations under neutral pH.
Price: On request

HEA HyperCel resin is a scalable chromatography resin designed for industrial use, capturing proteins and removing impurities in biopharmaceutical applications. Operating on a "mixed-mode" mechanism with a hexylamine ligand, its behavior is based on a combination of electrostatic and hydrophobic interactions between proteins and ligands. HEA HyperCel resin offers unique selectivity, different from that provided by ion exchange or conventional hydrophobic interaction chromatography (HIC).

Features & Benefits:

  • High mechanical and chemical stability
  • Suitable for chromatography in biopharmaceutical environments
  • Cross-linked cellulose base matrix

Applications:

  • Protein purification at low ionic strength via direct hydrophobic capture
  • Separation of challenging mixtures, e.g., protein isoforms or proteins with very close pl values
  • Orthogonal separation mechanism to ion exchange or HIC

Datasheet: HEA and PPA HyperCel Resins Mixed-mode Chromatography for Protein Separation