HEA HyperCel resin is a scalable chromatography resin designed for industrial use, capturing proteins and removing impurities in biopharmaceutical applications. Operating on a "mixed-mode" mechanism with a hexylamine ligand, its behavior is based on a combination of electrostatic and hydrophobic interactions between proteins and ligands. HEA HyperCel resin offers unique selectivity, different from that provided by ion exchange or conventional hydrophobic interaction chromatography (HIC).