CMM HyperCel | Mixed-Mode Chromatography Resins

CMM HyperCel resin consists of a rigid cellulose matrix with flow properties compatible with the needs of large-scale protein production. The proprietary ligand, containing both a primary amino and a carboxyl group, provides the chromatographic resin with cation exchange and hydrophobic properties. The ligand’s flexibility allows the separation of proteins with a wide range of isoelectric points and hydrophobicity levels, making it possible to use multiple conditions for isolating target molecules from contaminants.

Features & Benefits:

• Unique selectivity
• High-capacity mixed-mode chromatography resin
• High recovery, low elution volume
• Easy CIP, stable in NaOH

Applications:

• Capture of MAbs, Fab fragments, and recombinant proteins from challenging feedstocks
• Separation of proteins with similar isoelectric points and/or hydrophobicity at low or high conductivity