CIMac™ Analytical Columns
CIMac™ Analytical Columns combine all the characteristics of CIM® monoliths at analytical scale. They are a perfect tool for analysis and control of manufacturing processes, and ideal for process analytical technology (PAT). Designed for fast and reproducible HPLC monitoring and quantitation of proteins, viruses, pDNA, and other large biomolecules. These columns allow high-resolution separations with quantity and purity information delivered in minutes.
Price: On request
CIMac™ analytical columns are primarily designed for in-process and final control of different samples at different stages of the purification process. They can operate at high volumetric flow rates (1 to 20 column volumes/min), so information on the amount and purity of the product can be obtained within minutes.
Key benefits:
- analytical HPLC columns for nucleic acids, viral vectors,
viruses, and other biomolecules - in-process analysis and quantitation, and final product
control - at-line monitoring and control of manufacturing processes
- high sensitivity, accuracy and reproducibility
- no sample carryover
CIMac columns have a volume of 0.1 mL (0.3 for CIMac pDNA), can be run at flows from 1 to 30 column volumes/minute (varies by type), and have application optimized channel widths. CIMac columns are available in
19 different chemistries.
Application Note: Comparison of HIC Monolithic Support for Sample Displacement Chromatography of pDNA
Datasheet: CIMac Analytical Columns - Monolithic Columns for Large Biomolecule HPLC Analytics
Poster: Combining the Sensitivity of the PATfix® HPLC Platform With Ultracentrifugation for AAV Characterization
Poster: Fast HPLC Analytics for IVT Reaction Characterization and Tracking Using CIMac PrimaS™ and PATfix®
