In the production of gene therapy and vaccines, ensuring purity during further processing is particularly challenging. Rapid and efficient monitoring of targeted biomolecules and removal of impurities is critical, as it directly affects product yield and purity. Sartorius analytical chromatography solutions can help provide this information in real time, by tracking large biomolecules on the line including viruses, pDNA and mRNA. HPLC analytical chromatography on the line is performed using CIM® monolithic technology. Using CIMac® analytical columns, the PATfix® HPLC system provides 'in-line' analysis to control impurities and critical quality components.
