CIMmultus® QA for AAV and other viral vectors
CIMmultus® QA is a monolith for ion chromatography (IEX).
Price: On request
CIMmultus ® is a unique and industrially proven line of pre-packaged chromatography monolithic columns with high flow channels, designed to work with large biomolecules such as viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), nucleic acids (mRNA, pDNA), viral and exosomes. CIMmultus® columns can be used as disposable or single-use columns.
CIMmultus® monoliths are high-resolution chromatography devices designed for multiple scalable purification of complex biological samples. Inside the specially designed housing is a one-piece stationary phase with a homogeneous channel size and surface chemistry. This stationary phase is designed to simplify the transfer of methods from development to production.
Product features:
- strong anion exchanger
- working range, pH 2–13
- binds molecules with predominantly negative charge, repels molecules with predominantly positive charge
- capture, intermediate, or polishing steps in either bind-elute or flow-through mode
- high capacity for virus particles, IgM, exosomes
- high-efficiency removal of endotoxin and DNA
- outstanding for preparative applications or analytical fingerprinting of process samples
- sanitizable with 1 M NaOH
Application Note: Increasing Productivity of pDNA DSP Using Sample Displacement Chromatography
Application Note: Purification of mRNA by Affinity Chromatography on CIMmultus® Oligo dT Column
Application Note: Recovery of pDIKE2 Plasmid for Hepatitis C Vaccine Using CIMmultus® C4 HLD Monolith
Datasheet: CIMmultus® Monolithic Columns - Pre-Packed Preparative Columns for Purification of Large Biomolecules
