Biostat® B | Benchtop Bioreactor
Designed to meet your specific needs, Biostat® B covers a wide range of applications, from use as a flexible basic unit for clinical research to a fully qualified system that meets the requirements of a certified GMP environment. You can use our Biostat® B for growing animal, plant and insect cells, as well as for microbiological fermentation.
System benefits:
- mixing and rocking, reusable and disposable culture vessels - all controlled by a single DCU tower
- single or double setting to control one or two breeding vessels
- gas generation system comparable to our Biostat STR® with up to four mass flow regulators.
Proven efficiency of breeding vessels and advanced automation
Univessel® Glass
Our borosilicate glass culture vessels can be autoclaved and are available in four different quantities: 1 L, 2 L, 5 L and 10 L for all types of cell cultures and microbiological applications.
- the classic design of the mixing tank simplifies your scale-up and scale-down studies
- an extensive package of performance and engineering data is available
- our special design for small autoclaves
Univessel® SU
Our 2 L working capacity mixing vessel for use in cell culture combines a scalable design with all the advantages of a disposable solution. No more worries about challenging deadlines, workload or cross-contamination. Start in a few minutes.
- completely disposable container. DO and pH sensors
- proven, scalable mixing tank design
- connection kit for upgrading existing bioreactor regulators
RM Rocker
Our bioreactor consists of a swinging platform with a Flexsafe® RM bag carrier in the form of a cushion for a culture volume of 100 mL to 25 L. Use it as a basic system or in combination with the Biostat® B control tower and disposable optical pH and DO sensors that enable advanced batch, batch, and continuous perfusion management strategies.
- a simple platform with advanced alarms and security features for reliable processing
- space saving, individual control of two RM bags on the same platform
- built-in sustainable biomass measurement for reduced sampling needs and pollution risk
Automatic input control
Design your process strategy or choose different options. Configure your Biostat® B with gravimetric input control, gravimetric level control or substrate addition profiles. This allows you to run your Biostat® B in batch, continuous or perfusion mode.
Automatic dissolved oxygen (DO) control
In addition to the classic DO control, we have developed a unique advanced DO controller that gives you more flexibility to develop and optimize your DO management strategy. The advanced DO controller supports the parallel adjustment of all DOs that affect parameter settings such as agitator speed and airflow rate and pure oxygen.
Application of Biostat® B system in cell culture
1. BIOSTAT® B S UNIVESSEL® GLASS + BIOPAT® TRACE
- internet glucose measurement lactate
- real-time glucose concentration data available in monitoring software
2. BIOSTAT® B S UNIVESSEL® GLASS + BIOPAT® VIAMASS
- operate the BioPAT® Viamass probe without any external software
- monitor the viable cell volume directly on the local control screen
- information on sustainable cell volume available in monitoring software
3. BIOSTAT® B S RM ROCKER + BIOPAT® VIAMASS
- inline measurement of concentration and growth rate in real time
- disposable sensor disk integrated into Flexsafe® RM bags
- biomass monitoring in vaccine and regenerative medicine
